Validation of SMS Protocol for HCC Screening in High-risk Patients

Enrolling by invitationOBSERVATIONAL
Enrollment

470

Participants

Timeline

Start Date

November 7, 2023

Primary Completion Date

June 1, 2026

Study Completion Date

June 1, 2026

Conditions
Hepatocellular Carcinoma
Interventions
RADIATION

Short MRI surveillance (SMS) protocol

Bi-annual, non-contrast agents, MRI screening consisting of Diffusion Weighted Imaging (b-values of 50 and 800 s/mm2), T2-weighted imaging and T1-weighted in- and out-of-phase imaging

RADIATION

Bi-annual ultrasonography screening

Bi-annual ultrasonography for screening of HCC in high-risk patients

Trial Locations (6)

1105AZ

Academic Medical Center, Amsterdam

7512KZ

Medisch Spectrum Twente, Enschede

3318AT

Albert Schweitzer Ziekenhuis, Dordrecht

3015GD

Erasmus Medical Center, Rotterdam

3045PM

St. Franciscus Gasthuis & Vlietland, Rotterdam

3079DZ

Maasstad Ziekenhuis, Rotterdam

Sponsors
All Listed Sponsors
lead

Erasmus Medical Center

OTHER