Phase 1/2 Study of ISB 1442 in Relapsed/Refractory Multiple Myeloma

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

September 27, 2022

Primary Completion Date

November 19, 2024

Study Completion Date

November 19, 2024

Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
DRUG

ISB 1442 SC injection escalating doses

Participants will receive escalating SC doses of ISB 1442

DRUG

ISB 1442 SC injection at RP2D

ISB 1442 SC injection dose regimen at RP2D until participants experience disease progression or unacceptable toxicity, or until any other discontinuation criterion is met

Trial Locations (15)

2050

Royal Prince Albert Hospital: Institute of Haematology, Camperdown

3004

The Alfred Hospital-Melbourne, Melbourne

3065

St. Vincent's Hospital Melbourne, Fitzroy

4211

Gold Coast University Hospital, Southport

4217

Pindara Private Hospital, Benowa

6009

One Clinical Research Pty Ltd, Nedlands

10065

New York-Presbyterian /Weill Cornell Medical Center - The Myeloma Center, New York

33136

University of Miami - Sylvester Comprehensive Cancer Center, Miami

48201

Barbara Ann Karmanos Cancer Institute - Karmanos Cancer Center - Main Campus, Detroit

53226

Froedtert Hospital & The Medical College of Wisconsin, Milwaukee

60637

The University of Chicago Medical Center (UCMC) Duchossois Center for Advanced Medicine (DCAM), Chicago

63110

Washington University School of Medicine - Siteman Cancer Center, St Louis

Unknown

Health Care Global Enterprises Limited (HCG), Bangalore

M S Ramaiah Medical College & Hospital, Bangalore

Max Super Speciality Hospital, Delhi

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Ichnos Sciences SA

INDUSTRY

NCT05427812 - Phase 1/2 Study of ISB 1442 in Relapsed/Refractory Multiple Myeloma | Biotech Hunter | Biotech Hunter