Titanium Reinforced d-PTFE Membrane Versus Collagen Membrane For Guided Bone Regeneration

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2028

Conditions
Alveolar Ridge Enlargement
Interventions
DEVICE

collagen membrane (Creos Xenoprotect , Nobel Biocare AB, Göteborg, Sweden)

A mucoperiosteal flap will be raised with two vertical releasing on each side of the edentulous space. Autogenous bone chips are harvested from the retromolar area with bone scrapers and/or from an edentulous site using ACM bone collector. DBBM particles soaked in blood are mixed with autogenous bone chips to a ratio of 1:1. After having made multiple bone perforations at the buccal aspect of the recipient site, the mixture of bone chips and DBBM is applied. An individualized collagen membrane is attached on top using membrane fixation pins. Prior to fixation of the final pin, bone grafting material is additionally applied from the lateral aspect to ensure that it is properly packed under the membrane and fully stable. Following release of the periosteum and muscle insertion, tension-free primary wound closure is achieved.

DEVICE

titanium reinforced d-PTFE membrane (Creos Syntoprotect , Nobel Biocare AB, Göteborg, Sweden)

A mucoperiosteal flap will be raised with two vertical releasing on each side of the edentulous space. Autogenous bone chips are harvested from the retromolar area with bone scrapers and/or from an edentulous site using ACM bone collector. DBBM particles soaked in blood are mixed with autogenous bone chips to a ratio of 1:1. After multiple bone perforations at the buccal aspect of the recipient site, the mixture of bone chips and DBBM is applied.A titanium reinforced d-PTFE membrane is attached on top using membrane fixation pins. Care is taken to leave a distance of at least 1 mm between the membrane and neighboring teeth. Prior to fixation of the final pin, bone grafting material is additionally applied from the lateral aspect to ensure that it is properly packed under the membrane and fully stable. Following release of the periosteum and muscle insertion, tension-free primary wound closure is achieved. The membrane is removed after 9 months, prior to implant placement.

Trial Locations (3)

9000

RECRUITING

Universitair Ziekenhuis Gent, Ghent

9052

RECRUITING

Parodonto, Zwijnaarde

9620

RECRUITING

Centrum voor Parodontologie en Orale Implantologie, Zottegem

All Listed Sponsors
lead

University Ghent

OTHER