A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

167

Participants

Timeline

Start Date

August 18, 2022

Primary Completion Date

June 12, 2026

Study Completion Date

July 30, 2027

Conditions
Lymphoma, Non-HodgkinLeukemia, Lymphocytic, Chronic, B-Cell
Interventions
DRUG

JNJ-80948543

JNJ-80948543 will be administered as SC or IV injection.

Trial Locations (29)

2031

Scientia Clinical Research, Randwick

2100

Rigshospitalet, Copenhagen

2109

Macquarie University Hospital, Macquarie University

3004

The Alfred Hospital, Melbourne

5000

Odense University Hospital, Odense

6009

Linear Clinical Research Ltd, Nedlands

10029

Icahn School of Medicine at Mount Sinai, New York

10065

Memorial Sloan Kettering Cancer Center, New York

31059

Institut Universitaire du cancer de Toulouse-Oncopole, Toulouse

34362

Carmel Medical Center, Haifa

37203

Sarah Cannon Research Institute, Nashville

59037

CHRU de Lille Hopital Claude Huriez, Lille

64239

Tel Aviv Sourasky Medical Center, Tel Aviv

67033

Institut de Cancerologie Strasbourg Europe ICANS, Strasbourg

75005

Institut Curie, Paris

77030

The University of Texas MD Anderson Cancer Center, Houston

78229

Texas Transplant Institute, San Antonio

91010

City of Hope, Duarte

98109

Seattle Cancer Care Alliance, Seattle

300060

Tianjin cancer hospital, Tianjin

400044

Chongqing University Cancer Hospital, Chongqing

430030

Union Hospital Tongji Medical College of Huazhong University of Science and Technology, Wuhan

510060

Sun Yat Sen University Cancer Center, Guangzhou

9112001

Hadassah Medical Center, Jerusalem

277 8577

National Cancer Center Hospital East, Kashiwa

464 8681

Aichi Cancer Center, Nagoya

135 8550

The Cancer Institute Hospital of JFCR, Tokyo

80 214

Uniwersyteckie Centrum Kliniczne Osrodek Badan Klinicznych Wczesnych Faz, Gdansk

60-185

Aidport Sp z o o, Skorzewo

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY