Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant

PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

February 22, 2024

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
NAFLD
Interventions
DRUG

Semaglutide Pen Injector

Starting dose of 0.24 mg injected weekly and increased every 4 weeks to a potential maximum dose of 2.4 mg weekly at 20 weeks followed by 52 weeks of weekly injections at the maximum tolerable dose

DRUG

Placebo

Placebo solution injected weekly for 72 weeks

Trial Locations (1)

23298

RECRUITING

Virginia Commonwealth University, Richmond

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novo Nordisk A/S

INDUSTRY

lead

Virginia Commonwealth University

OTHER