Dose Ranging Study of Amlitelimab in Adult Participants With Moderate-to-severe Asthma

PHASE2CompletedINTERVENTIONAL
Enrollment

446

Participants

Timeline

Start Date

June 30, 2022

Primary Completion Date

October 11, 2024

Study Completion Date

March 20, 2025

Conditions
Asthma
Interventions
DRUG

Amlitelimab

Injection solution Subcutaneous injection

DRUG

Placebo

Injection solution Subcutaneous injection

Trial Locations (113)

1033

Investigational Site Number : 3480007, Budapest

1055

Investigational Site Number : 7100004, Middelburg

1060

Investigational Site Number : 0320009, Buenos Aires

1401

Investigational Site Number : 7100008, Johannesburg

1501

Investigational Site Number : 7100007, Benoni

2000

Investigational Site Number : 0320006, Rosario

2100

Investigational Site Number : 3480011, Gödöllö

2440

Investigational Site Number : 3480012, Százhalombatta

3780

Investigational Site Number : 3480009, Edelény

4071

Investigational Site Number : 7100003, Durban

4080

Investigational Site Number : 3480002, Hajdunánás

4150

Investigational Site Number : 3480006, Püspökladány

6530

Investigational Site Number : 7100006, George

7530

Investigational Site Number : 7100002, Cape Town

Investigational Site Number : 7100005, Cape Town

7937

Investigational Site Number : 7100001, Cape Town

9200

Investigational Site Number : 3480004, Mosonmagyaróvár

9700

Investigational Site Number : 3480003, Szombathely

13620

Investigational Site Number : 4100007, Seongnam-si, Gyeonggi-do

21224

Johns Hopkins University School of Medicine Site Number : 8400012, Baltimore

31000

Investigational Site Number : 4840002, Chihuahua City

33023

Pines Care Research Center LLC Site Number : 8400028, Pembroke Pines

33070

Investigational Site Number : 7920002, Mersin

33126

Savin Medical Group, LLC Site Number : 8400015, Miami

33157

Beautiful Minds Clinical Research Center Site Number : 8400027, Cutler Bay

33435

Helix Biomedics, LLC Site Number : 8400029, Boynton Beach

33991

Renaissance Research and Medical Group, Inc Site Number : 8400030, Cape Coral

34080

Investigational Site Number : 4840004, Durango, Durango

34303

Investigational Site Number : 7920001, Istanbul

35100

Investigational Site Number : 7920003, Izmir

37134

Investigational Site Number : 3800001, Verona

38039

Investigational Site Number : 7920008, Kayseri

41100

Investigational Site Number : 7920005, Kocaeli

42415

Investigational Site Number : 4100004, Daegu

43617

Asthma and Allergy Center Site Number : 8400005, Toledo

44100

Investigational Site Number : 4840001, Guadalajara

44124

Investigational Site Number : 3800002, Cona (FE)

44670

Investigational Site Number : 4840005, Guadalajara

46617

The South Bend Clinic, LLC Site Number : 8400033, South Bend

48034

Headlands Research Detroit Site Number : 8400032, Southfield

54055

Investigational Site Number : 4840006, Tlalnepantla

66103

University of Kansas Medical Center Site Number : 8400016, Kansas City

73034

OK Clinical Research, LLC Site Number : 8400001, Edmond

73120

Allergy, Asthma and Clinical Research Center Site Number : 8400035, Oklahoma City

78006

TTS Research Site Number : 8400011, Boerne

80131

Investigational Site Number : 3800004, Napoli

80344

Investigational Site Number : 6160002, Gdansk

83706

Treasure Valley Medical Research Site Number : 8400031, Boise

89052

Henderson Clinical Trials Site Number : 8400037, Henderson

90025

California Allergy and Asthma Medical Group, Inc. Site Number : 8400002, Los Angeles

92683

Allianz Research Institute Site Number : 8400023, Westminster

95117

Allergy Asthma Associates of Santa Clara Valley Site Number : 8400019, San Jose

95207

Bensch Clinical Research LLC Site Number : 8400004, Stockton

97070

Investigational Site Number : 4840008, Yucatán

2260877

Investigational Site Number : 1520005, Quillota

7500010

Investigational Site Number : 1520007, Santiago

7500692

Investigational Site Number : 1520001, Santiago

7500698

Investigational Site Number : 1520002, Santiago

7640881

Investigational Site Number : 1520009, Santiago

8380465

Investigational Site Number : 1520008, Santiago

8910131

Investigational Site Number : 1520003, Santiago

92093-0990

University of California San Diego Health Site Number : 8400026, La Jolla

33012-5853

Reliable Clinical Research, LLC Site Number : 8400020, Hialeah

C1425BEN

Investigational Site Number : 0320001, CABA

C1425FVH

Investigational Site Number : 0320002, CABA

B1900BNN

Investigational Site Number : 0320008, La Plata

S2000DEJ

Investigational Site Number : 0320007, Rosario

S2000JKR

Investigational Site Number : 0320005, Rosario

C1121ABE

Investigational Site Number : 0320004, Buenos Aires

C1414AIF

Investigational Site Number : 0320003, Ciudad Autonoma Buenos Aires

29055 450

CEDOES - Centro de Diagnostico e Pesquisa de Osteoporose do ES Site Number : 0760002, Vitória

40060-330

Proar Site Number : 0760004, Salvador

59062-000

Centro Avancado de Oncologia CECAN - Liga Contra o Cancer Site Number : 0760010, Natal

99010-120

Instituto Mederi de Pesquisa e Saude Site Number : 0760001, Passo Fundo

90020-090

Irmandade da Santa Casa de Misericordia de Porto Alegre Site Number : 0760007, Porto Alegre

90610-000

Hospital Sao Lucas da PUCRS Site Number : 0760006, Porto Alegre

05403-000

Hospital das Clinicas de Sao Paulo Site Number : 0760008, São Paulo

18040-425

Clinica de Alergia Martti Antila Site Number : 0760003, Sorocaba

L6T 0G1

Investigational Site Number : 1240006, Brampton

K1H 1E4

Investigational Site Number : 1240008, Ottawa

M5T 3A9

Investigational Site Number : 1240005, Toronto

G8T 7A1

Investigational Site Number : 1240007, Trois-Rivières

G1V 4G5

Investigational Site Number : 1240003, Québec

Unknown

Investigational Site Number : 1520006, Talca

Investigational Site Number : 4100006, Seoul

00168

Investigational Site Number : 3800003, Rome

286-8520

Investigational Site Number : 3920014, Narita-shi

247-0072

Investigational Site Number : 3920002, Kamakura-shi

223-0059

Investigational Site Number : 3920016, Yokohama

245-8575

Investigational Site Number : 3920006, Yokohama

783-8509

Investigational Site Number : 3920013, Nankoku-shi

860-8556

Investigational Site Number : 3920015, Kumamoto

591-8555

Investigational Site Number : 3920010, Sakai-shi

103-0022

Investigational Site Number : 3920017, Chuo-ku

103-0027

Investigational Site Number : 3920005, Chuo-ku

104-0031

Investigational Site Number : 3920004, Chuo-ku

204-8585

Investigational Site Number : 3920020, Kiyose-shi

140-8522

Investigational Site Number : 3920001, Shinagawa-ku

162-8655

Investigational Site Number : 3920011, Shinjuku-ku

190-0014

Investigational Site Number : 3920009, Tachikawa-shi

170-0003

Investigational Site Number : 3920018, Toshima-ku

811-1394

Investigational Site Number : 3920008, Fukuoka

730-0013

Investigational Site Number : 3920019, Hiroshima

60-693

Investigational Site Number : 6160001, Poznan

31-559

Investigational Site Number : 6160006, Krakow

15-044

Investigational Site Number : 6160004, Bialystok

82-300

Investigational Site Number : 6160003, Elblag

33-100

Investigational Site Number : 6160007, Tarnów

03312

Investigational Site Number : 4100003, Seoul

03722

Investigational Site Number : 4100001, Seoul

05030

Investigational Site Number : 4100005, Seoul

138-878

Investigational Site Number : 4100002, Seoul

BD9 6RJ

Investigational Site Number : 8260001, Bradford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Sanofi

INDUSTRY