A Study for the Adjuvant Treatment of Breast Cancer

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,413

Participants

Timeline

Start Date

July 10, 2022

Primary Completion Date

July 10, 2027

Study Completion Date

December 20, 2027

Conditions
Breast Cancer
Interventions
DRUG

Docetaxel

75 mg/m2, d1, q3w,6 cycles

DRUG

Carboplatin

AUC 6, d1, q3w,6 cycles

DRUG

Trastuzumab

starting dose 8 mg/kg, maintenance dose 6 mg/kg, d1, q3w,6 cycles

DRUG

Pertuzumab

starting dose of 840 mg, maintenance dose of 420 mg, d1, q3w ,6 cycles

DRUG

Nab paclitaxel

220 mg/m2, d1, q3w,6 cycles

DRUG

Epirubicin

90 mg/m2, d1, q3w ,4 cycles ,followed by docetaxel

DRUG

Cyclophosphamide

600 mg/m2, d1, q3w × 4 cycles followed by docetaxel

DRUG

Docetaxel

100 mg/m2, d1, q3w × 4 cycles

DRUG

Epirubicin

90 mg/m2,d1, q2w × 4 cycles followed by nab-paclitaxel

DRUG

Cyclophosphamide

600 mg/m2, d1, q2w × 4 cycles followed by nab-paclitaxel

DRUG

Nab paclitaxel

125 mg/m2, d1,8,15, q3w× 4 cycles

DRUG

Cyclophosphamide

600 mg/m2, d1, q3w × 6 cycles

Trial Locations (1)

310000

RECRUITING

2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou

All Listed Sponsors
lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

NCT05420467 - A Study for the Adjuvant Treatment of Breast Cancer | Biotech Hunter | Biotech Hunter