Up-front Matched Unrelated Donor Transplantation in Pediatric Patients With Idiopathic Aplastic Anemia

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

June 30, 2022

Primary Completion Date

August 31, 2025

Study Completion Date

June 30, 2027

Conditions
Idiopathic Aplastic AnemiaSevere Aplastic AnemiaModerate Aplastic Anemia Requiring Transfusions
Interventions
OTHER

HSCT Arm group

"Conditioning regimen Stem cell source Only Bone Marrow With a minimal target dose of 4x108 nucleated cells/kg recipient ideal body weight. If the graft is less rich than the minimum target dose, it can be administered at the discretion to the physician.~GVHD Prophylaxis Prevention of EBV reactivation : Rituximab 150mg/m2 IV at Day+5 post HSCT."

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER