Immunosuppression and COVID-19 Boosters

PHASE3RecruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

July 21, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
COVID-19
Interventions
BIOLOGICAL

diphtheria and tetanus toxoids (adsorbed) vaccine

The diphtheria/tetanus toxoids vaccine will be given to participants enrolled into Group 1 as a comparator vaccine to the mRNA COVID-19 booster vaccine with the aim of determining whether the results related to COVID-19 vaccine timing also apply to more traditional protein-based vaccines.

BIOLOGICAL

COVID-19 vaccine

All participants will receive a COVID-19 booster vaccination at either week 0 or week 24 depending on their randomised study arm

Trial Locations (5)

2010

RECRUITING

St Vincent's Hospital, Sydney, Darlinghurst

2050

RECRUITING

Royal Prince Alfred Hospital, Camperdown

2137

RECRUITING

Concord General Repatriation Hospital, Concord

2145

RECRUITING

Westmead Hospital, Westmead

2148

RECRUITING

Blacktown Hospital, Blacktown

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Seqirus Pty Ltd, Australia

UNKNOWN

collaborator

Medical Research Future Fund

OTHER

lead

Kirby Institute

OTHER_GOV