Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

PHASE1UnknownINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

September 30, 2022

Primary Completion Date

September 30, 2024

Study Completion Date

September 30, 2025

Conditions
Nasopharyngeal CarcinomaCastrate Resistant Prostate CancerGastric CancerOvarian Clear Cell CarcinomaMesotheliomaSarcomaNon Hodgkin LymphomaB Cell LymphomaEpithelioid Sarcoma
Interventions
DRUG

APG-5918

"The investigational drug product is formulated as oral tablets of 50 mg or 200 mg that contain APG-5918 as the active ingredient. APG-5918 will be orally administered once every day on 28-day cycles.~The dosage of APG-5918 depends on the dose level to which the patient is assigned. Each dose of APG-5918 will be taken orally in fasted condition in the study."

Trial Locations (1)

72762

RECRUITING

Highlands Oncology, Springdale

Sponsors
All Listed Sponsors
lead

Ascentage Pharma Group Inc.

INDUSTRY