Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Type 1 Diabetes Mellitus

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

September 5, 2022

Primary Completion Date

September 1, 2026

Study Completion Date

December 1, 2026

Conditions
Type 1 Diabetes
Interventions
COMBINATION_PRODUCT

ECP regular-intensity arm

"* Weeks 1-8: Once every 2 weeks: weeks 1, 3, 5, 7 (cryo-ECP bags infused twice-a-week)~* Weeks 9-16: Once per month: weeks 9, 13 (cryo-ECP bags infused once-a-week)~* Weeks 17-24: One: week 17 (cryo-ECP bags infused every two weeks)"

COMBINATION_PRODUCT

ECP accelerated-intensity arm

"* Weeks 1-8: Once every week: weeks 1- 7 (cryo-ECP bags infused twice-a-week)~* Weeks 9-16: Cryo-ECP bags infused once-a-week~* Weeks 17-24: Cryo-ECP bags infused every two weeks"

BIOLOGICAL

T1DM standard of care

"The standard of care is defined as per the DOH Standards for diagnosis, management and data reporting for diabetes in combination with the DOH recommended NICE guidelines Type 1 diabetes in adults: diagnosis and management (NG17)"

Trial Locations (1)

4600

RECRUITING

Abu Dhabi Stem Cells Center, Abu Dhabi

All Listed Sponsors
lead

Abu Dhabi Stem Cells Center

OTHER_GOV