Evaluation of 177Lu-TATE-EB-01(LNC1010)in SSTR2-positive Tumors

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

March 24, 2025

Study Completion Date

March 24, 2025

Conditions
SSTR2-positive Tumors
Interventions
DRUG

177Lu-LNC1010 1

The patients were intravenously injected with single dose 2.22GBq (60 mCi) of 177Lu-LNC1010 and underwent 68Ga-DOTA-TATE PET/CT scans before and after the treatment.

DRUG

177Lu-LNC1010 2

The patients were intravenously injected with single dose 3.33GBq (90 mCi) of 177Lu-LNC1010 and underwent 68Ga-DOTA-TATE PET/CT scans before and after the treatment.

DRUG

177Lu-LNC1010 3

The patients were intravenously injected with single dose 4.99GBq (135 mCi) of 177Lu-LNC1010 and underwent 68Ga-DOTA-TATE PET/CT scans before and after the treatment.

DRUG

177Lu-LNC1010 4

Patients received a single, fixed dose of 177Lu-LNC1010 via intravenous injection, utilizing the well-tolerated and safe dose identified in Phase 1. They also underwent 68Ga-DOTA-TATE PET/CT scans both before and after the treatment to monitor their response.

Trial Locations (1)

361000

The First Affiliated Hospital of Xiamen University, Xiamen

All Listed Sponsors
lead

The First Affiliated Hospital of Xiamen University

OTHER