1,176
Participants
Start Date
August 1, 2022
Primary Completion Date
September 12, 2023
Study Completion Date
October 1, 2023
Detection of fecal samples with diagnostic kit
The 23S rRNA mutation site of clarithromycin and gyrA mutation site of levofloxacin were detected by Helicobacter Pylori fecal Gene Mutation Detection Kit.
Sanger Sequencing group
Detection of gyrA and 23S rRNA mutations in H. pylori isolated from Gastric Mucosa by Sanger Sequencing
Bacterial culture and drug sensitivity test of gastric mucosa samples
First, a sample of the patient's gastric mucosa will be obtained through gastroscopy. Then, Helicobacter pylori culture and drug sensitivity test can be carried out. Finally, the resistance data of Helicobacter pylori to clarithromycin and levofloxacin will be obtained.
Nanjing First Hospital, Nanjing Medical University, Nanjing
Jiangsu Taizhou People's Hospital, Taizhou
The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou
The First Affiliated Hospital of Nanchang University, Nanchang
Nanjing First Hospital, Nanjing Medical University
OTHER