The Poor Responders Study

NARecruitingINTERVENTIONAL
Enrollment

220

Participants

Timeline

Start Date

August 1, 2018

Primary Completion Date

September 1, 2027

Study Completion Date

September 1, 2027

Conditions
Bariatric Surgery CandidateObesity, MorbidDiabetes Mellitus, Type 2
Interventions
OTHER

Gut hormones

"Their first visit will act as an acclimatisation visit and participants will be infused subcutaneously with a triple gut hormone infusion (GLP-1, PYY and OXM). This will not only allow us to acclimatise the study volunteer to the study visits, but also allow us to test for subject tolerability of the gut hormones.~For the next two visits participants will be randomised in a single-blinded fashion to a subcutaneous infusion of either:~1. 0.9% saline,~2. GLP-1"

Trial Locations (1)

W120NN

RECRUITING

Imperial College London, London

All Listed Sponsors
lead

Imperial College London

OTHER