40
Participants
Start Date
March 13, 2023
Primary Completion Date
January 1, 2026
Study Completion Date
January 1, 2027
Autologous matrix-induced chondrogenesis (AMIC)
AMIC is a novel approach in which the microfracture technique has been enhanced by the use of a type I/III collagen matrix (Chondro-Gide®; Geistlich Pharma AG, Wolhusen, Switzerland). In this single-step procedure, the matrix is placed over the defect to stabilize the fragile blood clot that arises from microfracture and to provide infrastructure for repair tissue formation. Essentially, the matrix covers the defect and serves as a protective shield that contains the cells and minimizes the impact of shear forces when moving the hip on the delicate blood clot. At the same time, it functions as the roof of a biological chamber that forms over the defect. The biocompatible collagen material provides an environment for cell growth and is replaced by native tissue over time.
RECRUITING
McMaster University, Hamilton
Collaborators (1)
Geistlich Pharma AG
INDUSTRY
McMaster University
OTHER