Canakinumab for the Treatment of Postprandial Hypoglycemia

PHASE3RecruitingINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

April 17, 2023

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
Postprandial Hypoglycemia
Interventions
DRUG

Canakinumab

Canakinumab (Ilaris®, Novartis Switzerland) will be used in the recommended standard dose of 150 mg subcutaneously once. Patients will be randomized at visit 2 = Baseline to either placebo (1 ml 0.9 % saline solution s.c.) or treatment with 1 ml 150 mg canakinumab solution s.c. in a 1:1 manner.

DRUG

Placebo (0.9% NaCl)

1 ml 0.9 % saline solution s.c. Patients will be randomized at visit 2 = Baseline to either placebo (1 ml 0.9 % saline solution s.c.) or treatment with 1 ml 150 mg canakinumab solution s.c. in a 1:1 manner.

Trial Locations (2)

4031

RECRUITING

University Hospital Basel, Division of Endocrinology, Diabetes and Metabolism, Basel

4600

RECRUITING

Cantonal Hospital Olten, Division of Endocrinology, Olten

All Listed Sponsors
lead

University Hospital, Basel, Switzerland

OTHER