Association of Silicone Breast Implants With Overall Wellbeingand Auto-immune Diseases

UnknownOBSERVATIONAL
Enrollment

15,000

Participants

Timeline

Start Date

July 1, 2022

Primary Completion Date

June 1, 2024

Study Completion Date

June 1, 2025

Conditions
Breast CancerBreast Implant; ComplicationsAutoimmune Diseases
Interventions
PROCEDURE

Breast reconstruction with silicone breast implant

(i) mastectomy followed by immediate implant-based reconstruction, (ii) mastectomy followed by implant-based reconstruction at a later stage and (iii) latissimus dorsi flap reconstruction with a silicone breast implant.

PROCEDURE

Breast conserving surgery/Mastectomy/Autologous reconstruction

(iv) simple mastectomy without reconstruction, (v) autologous reconstruction and (vi) breast conserving surgery,

PROCEDURE

Breast Augmentation

(vii) cosmetic augmentation with silicone breast implants

Trial Locations (7)

Unknown

Zuyderland Medical Center, Heerlen

Maastricht University Medical Center, Maastricht

Netherlands Cancer Institute Antoni van Leeuwenhoek, Amsterdam

Velthuis Kliniek, Hilversum

Ziekenhuisgroep Twente, Almelo

Medisch Spectrum Twente, Enschede

Erasmus MC University Medical Center, Rotterdam

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Erasmus Medical Center

OTHER

collaborator

Maastricht University Medical Center

OTHER

collaborator

Zuyderland Medical Centre

OTHER

collaborator

Medisch Spectrum Twente

OTHER

collaborator

Ziekenhuisgroep Twente

OTHER

collaborator

Velthuis Kliniek

UNKNOWN

lead

The Netherlands Cancer Institute

OTHER