Efficacy and Safety in Transfusion Independent Non-severe Aplastic Anemia

PHASE2CompletedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

December 19, 2022

Primary Completion Date

February 1, 2025

Study Completion Date

April 15, 2025

Conditions
Aplastic Anemia
Interventions
DRUG

Luspatercept

Patients in each group will be treated for at least 6 months and continue the treatment for an additional 6 months unless disease progress or have intolerable side effects.

DRUG

Cyclosporine

Cyclosporine was administered at a 3-5 mg/(kd/d) and maintained at a 100-200 ng/ml trough plasma concentration.

Trial Locations (1)

Unknown

Peking union medical college hospital, Beijing

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Bing Han

OTHER