Comparison Between Hyperoncotic and Isooncotic Albumin to Support Blood Loss Replacement

PHASE4CompletedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

May 25, 2022

Primary Completion Date

March 30, 2023

Study Completion Date

April 10, 2023

Conditions
Blood Loss, SurgicalFluid Retention
Interventions
DRUG

Hyperoncotic Albumin 20%

Intravenous administration during removal of the bladder (i.e. the bleeding part) of cystectomy procedures.

DRUG

Isooncotic Albumin 5%

Intravenous administration of Albumin 5% 12ml/kg (ideal body weight) completed by a Ringer-lactate crystalloid ratio 1:1 to total amount of blood loss during removal of the bladder (i.e. the bleeding part) of cystectomy procedures.

DRUG

Ringer's Lactate Crystalloid Solutions (control group)

Intravenous administration of Ringer-lactate ratio 3:1 of total of blood loss during removal of the bladder (i.e. the bleeding part) of cystectomy procedures.

Trial Locations (1)

3010

Patrick Wuethrich, Department of Anaesthesiology and Pain Therapy, University Hospital Bern Inselspital Bern, Bern

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER