NCT05388968 - Metatranscriptomic Next Generation Sequencing in First Trimester Trophoblast With Increased Fetal Nuchal Translucency (METAHCN) | Biotech Hunter

Enrollment

110

Participants

Timeline

Start Date

November 7, 2022

Primary Completion Date

May 31, 2025

Study Completion Date

February 28, 2026

Conditions

Increased Nuchal Translucency in the First Trimester of Pregnancy

Interventions

BIOLOGICAL

Metatranscriptomic

Analysis with metatranscriptomic next generation sequencing of trophoblast obtained by chorionic villi sampling

DIAGNOSTIC_TEST

Specific microbiologic diagnosis

If a microorganism is detected by metatranscriptomic NGS, specific diagnosis (PCR and serology) will be done in maternal and neonatal samples (blood, urine, saliva)

Trial Locations (1)

75015

RECRUITING

Hopital Necker - Enfants malades, Paris