450
Participants
Start Date
June 3, 2022
Primary Completion Date
June 1, 2026
Study Completion Date
June 1, 2027
Prescreening
Eligible patients (history of early stage breast cancer and at least 3 months from completion of local and systemic therapy at Johns Hopkins, reads and speaks English) complete survey for demographics, smoking status \& questions about cardiovascular disease.
Screening and Enrollment
Consent
Baseline
Behavioral Battery and Patient Reported Outcome Quality of Life questionnaires (EORTC QLQ-C30 and QLQ-BR23) Labs (Hba1c + lipid panel if not done within 12 months or if abnormal within 1 year) Abstract vitals from chart review
Interpret BMI
Refer to Healthful Eating, Activity and Weight Program (HEAWP) if BMI ≥25 and not already on lifestyle intervention
Interpret HbA1c
"HbA1c results categorized as follows:~HbA1c \<5.7%; HbA1c 5.7-6.4%; HbA1c 6.5%+; or Known diabetic on medication"
Interpret lipid panel and assess other risk factors
"Based on above categories:~HbA1c \<5.7%: Any of these cardiovascular disease risk factors: current/former tobacco use, total cholesterol \>200, family history of Coronary Artery Disease/Heart Attack in first degree family \<55 year old male or \<65 year old female, systolic blood pressure \>130 HbA1c 5.7-6.4%: Refer to Primary Care Provider and consider Healthful Eating, Activity and Weight Program (HEAWP) HbA1c 6.5%+: Refer to Endocrinology if HbA1c ≥8% Known diabetic on medication: Refer to Endocrinology if HbA1c ≥7%"
Assess 10 year risk of cardiovascular event
If risk factors are present - refer to Cardiovascular Disease Prevention Program
Recommendations
Provide individual patient handout based on all above interventions
Follow-Up
6 and 12 month labs (if prior abnormal) and Patient Reported Outcome questionnaires
RECRUITING
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
Private Philanthropic Funds
OTHER
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
OTHER