A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

183

Participants

Timeline

Start Date

May 18, 2022

Primary Completion Date

June 14, 2024

Study Completion Date

June 14, 2024

Conditions
Dyslipidemia
Interventions
DRUG

AZD0780

Subjects will receive AZD0780 orally as a single ascending dose.

DRUG

AZD0780

Subjects will receive AZD0780 orally as a multiple ascending dose.

DRUG

AZD0780

Subjects will receive AZD0780 orally as a single and multiple ascending dose.

DRUG

Placebo

Subjects will receive placebo matching the AZD0780 dose orally as a single ascending dose.

DRUG

Placebo

Subjects will receive placebo matching the AZD0780 dose orally as a multiple ascending dose.

DRUG

Placebo

Subjects will receive placebo matching the AZD0780 dose orally as a single and multiple ascending dose.

DRUG

Rosuvastatin

Subjects will receive rosuvastatin orally.

Trial Locations (3)

21225

Research Site, Brooklyn

91206

Research Site, Glendale

HA1 3UJ

Research Site, Harrow

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Parexel

INDUSTRY

lead

AstraZeneca

INDUSTRY