CD19 Chimeric Antigen Receptors and CD19 Positive Feeder T Cells as a Leukemia Consolidation Treatment

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 2, 2018

Primary Completion Date

August 2, 2024

Study Completion Date

December 1, 2025

Conditions
Acute Lymphoblastic Leukemia in Remission
Interventions
BIOLOGICAL

CD19 CAR-T cells and CD19 positive feeder T cells

Detailed Description: Patients were divided into two groups, group 1 and group 2, and each group was enrolled in 5 patients. Group 1 patients did not receive any pretreatment, and group 2 patients received pretreatment with cyclophosphamide and fludarabine prior to reinfusion. Then Patients were given Chimeric Antigen Receptor T-Cell ( CAR-T) and CD19-positive T cells.

Trial Locations (3)

200000

RECRUITING

The first affiliated hospital of soochow university, Suzhou

215006

RECRUITING

The first affiliated hospital of soochow university, Suzhou

Unknown

RECRUITING

The First Affiliated Hospital of Soochow University, Suzhou

All Listed Sponsors
collaborator

The First Affiliated Hospital of Soochow University

OTHER

lead

Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd

INDUSTRY