40
Participants
Start Date
June 21, 2022
Primary Completion Date
February 1, 2026
Study Completion Date
May 31, 2026
Consume 20mg of istradefylline
Consume a single 20 mg istradefylline tablet
Low Oxygen therapy
Breathing short periods of low oxygen, consisting of 15 episodes of 1 minute of breathing 10% oxygen, with 2 minutes of breathing 21% oxygen. 45 minutes total.
Placebo counterpart to the istradefylline drug
Consume a single microcrystalline cellulose
SHAM counterpart to low oxygen therapy.
Breathing short periods of sham low oxygen, consisting of 15 episodes of 1 minute of breathing 21% oxygen, separated by 2 minutes of breathing 21% oxygen. 45 minutes total.
RECRUITING
UF Health Jacksonville, Jacksonville
RECRUITING
Clinical and Translational Research Building, Gainesville
ALS Association
OTHER
University of Florida
OTHER