Pulmonary Vascular Dysfunction as a Cause of Persistent Exertional Dyspnea After Coronavirus Disease (COVID-19)

Active, not recruitingOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

April 15, 2022

Primary Completion Date

March 31, 2025

Study Completion Date

December 31, 2025

Conditions
COVID-19
Interventions
OTHER

pulmonary vascular dysfunction

Right ventricular function determined by echocardiography at rest and during exercise (non-invasive estimation of ventilation-perfusion mismatch), systemic endothelial function, left heart function, and plasma levels of vasoactive biomarkers compared with clinical parameters of dyspnea and exercise capacity. Further examinations will be performed in patients with still unclear cause of persistent shortness of breath after 3 months of follow-up (subgroup RHC)

OTHER

pulmonary vascular function

Right ventricular function determined by echocardiography at rest and during exercise (non-invasive estimation of ventilation-perfusion mismatch), systemic endothelial function, and plasma levels of vasoactive biomarkers compared with clinical parameters of dyspnea and exercise capacity.

Trial Locations (1)

Unknown

Natascha Sommer, Giessen

All Listed Sponsors
lead

University of Giessen

OTHER