NCT05373316View on ClinicalTrials.gov

Addition of a Focal Boost in External Beam Radiotherapy for Locally Advanced Prostate Cancer by Online Adaptive MR-guided Radiotherapy

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

95

Participants

Timeline

Start Date

December 1, 2022

Primary Completion Date

July 1, 2024

Study Completion Date

July 1, 2029

Conditions
Prostate CancerProstate Neoplasm
Interventions
RADIATION

Ultrahypofractionated MR-guided radiotherapy boost

External beam MR-guided (MR-linac) radiotherapy to the prostate and seminal vesicles of 5x7Gy (once weekly) with an isotoxic integrated focal boost up to 50Gy to the intraprostatic tumor as visible on multiparametric MRI.

Trial Locations (2)

6525GA

Radboudumc, Nijmegen

1066CX

Netherlands Cancer Institute, Amsterdam

All Listed Sponsors
lead

Radboud University Medical Center

OTHER

NCT05373316 - Addition of a Focal Boost in External Beam Radiotherapy for Locally Advanced Prostate Cancer by Online Adaptive MR-guided Radiotherapy | Biotech Hunter | Biotech Hunter