A Study Comparing Two Different Capsules, APL-101 and PLB-1001 Capsules, in Healthy Chinese and Caucasian Participants

PHASE1UnknownINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

May 20, 2022

Primary Completion Date

November 30, 2022

Study Completion Date

December 31, 2022

Conditions
Bioequivalence
Interventions
DRUG

APL-101

"APL-101 (Vebreltinib) is an orally available small molecule, which is a tyrosine kinase inhibitor (TKI) for the mesenchymal epithelial transition protein tyrosine kinase receptor (c-Met) with high selectivity and potency.~The treatments to be administered in this study include:~• Treatment A (reference): Two 100 mg APL-101 (Vebreltinib) capsules (200 mg dose), manufactured for Apollomics, Inc."

DRUG

PLB-1001

"PLB-1001 (Bozitinib) is a chemical drug category 1.1 innovative drug. It is a highly effective and highly selective c-Met tyrosine kinase inhibitor.~The treatments to be administered in this study include:~• Treatment P (test): Two 100 mg PLB-1001 (Bozitinib) capsules (200 mg dose), manufactured for Beijing Pearl Biotechnology Co., Ltd."

Trial Locations (1)

Unknown

RECRUITING

New Zealand Clinical Research, Auckland

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Apollomics Inc.

INDUSTRY