The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms

PHASE3RecruitingINTERVENTIONAL
Enrollment

252

Participants

Timeline

Start Date

August 22, 2022

Primary Completion Date

April 22, 2026

Study Completion Date

April 22, 2027

Conditions
Candidiasis, VulvovaginalRecurrent Candidiasis of Vagina
Interventions
DRUG

Fluconazole

"Way of administration: oral capsules. One capsule at the same day of the week.~Dosage:~As treatment for active RVVC- in the first week on day 1 one capsule 150 mg Fluconazole, on day 4 one capsule 150 mg Fluconazole and on day 7 one capsule 150 mg Fluconazole.~As prophylaxis to prevent a new RVVC episode: one capsule Fluconazol 150 mg per week for a duration of 6 months."

DEVICE

L-Mesitran

"Way of administration: intra-vaginal application using an applicator.~Dosage:~As treatment for active RVVC - Single daily application (5 grams) for 1 month. As prophylaxis to prevent a new RVVC episode: Single weekly (5 grams) application for 5 months."

Trial Locations (2)

Unknown

RECRUITING

Zuyderland Medical Centre, Heerlen

RECRUITING

MaastrichtUMC, Maastricht

All Listed Sponsors
lead

Maastricht University Medical Center

OTHER

collaborator

Zuyderland Medical Centre

OTHER