Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

July 25, 2022

Primary Completion Date

June 1, 2027

Study Completion Date

June 1, 2027

Conditions
Carcinoma, HepatocellularLiver Cell Carcinoma
Interventions
DRUG

Tislelizumab

Tislelizumab (also known as BGB A317) is a humanized, immunoglobulin G4 (IgG4)-variant monoclonal antibody against programmed cell death protein-1 (PD-1) under clinical development for the treatment of several human malignancies. Tislelizumab consolidation therapy after radiation therapy can capitalize on the immunomodulatory effect of radiotherapy and improve tumor responses and patient outcomes.

Trial Locations (2)

10451

RECRUITING

Montefiore Medical Center, The Bronx

08903

RECRUITING

Rutgers Cancer Institute of New Jersey, New Brunswick

All Listed Sponsors
collaborator

BioGene Pharmaceutical Ltd.

INDUSTRY

collaborator

Natera, Inc.

INDUSTRY

lead

Rutgers, The State University of New Jersey

OTHER

NCT05366829 - Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma | Biotech Hunter | Biotech Hunter