Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru

RecruitingOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

August 28, 2023

Primary Completion Date

October 31, 2024

Study Completion Date

October 31, 2024

Conditions
Malaria, Vivax
Interventions
OTHER

Training on revised algorithm

relevant HCP working in study facilities will be trained on the relevant aspects of performing the G6PD testing, interpreting its result, evaluating patient's eligibility for RC and choosing the appropriate treatment as per their role accordingly

OTHER

Enhancing Pharmacovigilance

Refresher training on PV reporting in the selected facilities. National PV forms will be reviewed and if required, modified in consultation with the national PV system.

OTHER

Supervision of malaria services in selected facilities.

Supervisors in target regions will be trained as for the HCPs.

DIAGNOSTIC_TEST

G6PD testing

G6PD test after Malaria Vivax diagnosis

DRUG

Tafenoquine

300 mg (2x150mg tablets) tafenoquine

DRUG

Primaquine

0.5mg/kg/7 days

OTHER

Follow Up Visit at Day 3 [+2 days] after treatment start

It will be checked if all patients have a Follow Up Visit at Day 3 \[+2 days\] after treatment start

Trial Locations (1)

16310

RECRUITING

Nauta Nucleo- Base, Nauta

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Universidad Peruana Cayetano Heredia

OTHER

collaborator

UNITAID

OTHER

collaborator

ICON plc

INDUSTRY

lead

Medicines for Malaria Venture

OTHER