Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis

NAActive, not recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 15, 2023

Primary Completion Date

December 18, 2024

Study Completion Date

September 30, 2025

Conditions
Insulin Sensitivity24-hour Glucose Control
Interventions
OTHER

HIgh UPF controlled diet

Following a two- week eucaloric lead-in diet, participants will be provided and consume a diet emphasizing UPF (81% energy). Diets will be eucaloric (50% carbohydrate, 35% fat,15% protein) matched for dietary soluble and insoluble fiber, added sugar, mono- and polyunsaturated fat, saturated fat, antioxidant nutrients, sodium, pre- and probiotics, and overall diet quality, for 6 weeks.

OTHER

No UPF controlled diet

Following a two- week eucaloric lead-in diet, participants will be provided and consume a diet without UPF (0% energy). Diets will be eucaloric (50% carbohydrate, 35% fat,15% protein) matched for dietary soluble and insoluble fiber, added sugar, mono- and polyunsaturated fat, saturated fat, antioxidant nutrients, sodium, pre- and probiotics, and overall diet quality, for 6 weeks.

Trial Locations (1)

24061

Virginia Tech, Blacksburg

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Duke University

OTHER

lead

Virginia Polytechnic Institute and State University

OTHER

NCT05358171 - Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis | Biotech Hunter | Biotech Hunter