A First-in-human (FIH) Combination Treatment Study With a Single Dose Level of BMC128

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

May 1, 2022

Primary Completion Date

May 31, 2024

Study Completion Date

November 30, 2025

Conditions
Non-small Cell Lung CancerMelanomaRenal Cell Carcinoma
Interventions
DRUG

BMC128

A live bio-therapeutic product composed of 4 commensal bacterial strains, natural inhabitants of the human intestinal tract.

DRUG

Nivolumab

A human monoclonal antibody that blocks programmed-death-1 (PD-1). It is a type of immunotherapy and works as a checkpoint inhibitor, blocking a signal that prevents activation of T cells from attacking the cancer.

Trial Locations (1)

Unknown

Rambam MC, Haifa

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Biomica Ltd.

INDUSTRY