Metastasis-directed Therapy for Oligorecurrent Prostate Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

873

Participants

Timeline

Start Date

April 20, 2022

Primary Completion Date

April 25, 2027

Study Completion Date

April 25, 2032

Conditions
Prostate CancerProstate Cancer RecurrentProstate Cancer MetastaticMetastatic CancerOligometastatic DiseaseOligometastasisHormone Sensitive Prostate Cancer
Interventions
OTHER

Radiotherapy (SBRT) and/or surgery (metastasectomy)

Metastasis-directed therapay (surgery and/or radiotherapy) as treatment for oligorecurrent lesions

DRUG

Androgen deprivation therapy

Arm B: gosereline 3.6 mg sc, leuproreline 7.5 mg sc, triptoreline 3.75 mg im Arm C: gosereline 3.6 mg sc 1x/month or gosereline 10.8 mg sc or leuproreline 7.5 mg sc 1x/month or leuproreline 45 mg sc or triptoreline 3.75 mg im 1x/month or triptoreline 11.5 mg im 1x/3months or triptoreline 22.5 mg im

DRUG

Androgen receptor targeted therapy

Enzalutamide

Trial Locations (1)

Unknown

RECRUITING

University Hospitals Leuven, Leuven

All Listed Sponsors
lead

Universitaire Ziekenhuizen KU Leuven

OTHER