Safety and Tolerability of Pirfenidone in Acute Pancreatitis

Patients in the pirfenidone treatment arm will be given pirfenidone 267mg tablet, tid for 1 day followed by dose escalation to two 267 mg tablet tid for 6 days. Thus, the treatment will be for total of 7 days or till patients develop an adverse event that requires their participation in the study to be stopped.

The placebo tablets will be an exact replica of the pirfenidone tablet.