Evaluation of Reporting of Antibody-Drug Conjugate Associated Sepsis-related Toxicities

CompletedOBSERVATIONAL
Enrollment

24,618

Participants

Timeline

Start Date

April 22, 2022

Primary Completion Date

May 22, 2022

Study Completion Date

June 1, 2022

Conditions
Sepsis (SMQ)Opportunistic InfectionsAgranulocytosis
Interventions
DRUG

Antibody-Drug Conjugate

"Compared the case reporting of sepsis-related toxicities among ADC and other common cancer drug therapies.~ADC:including Gemtuzumab Ozogamicin, Trastuzumab Emtansine, Inotuzumab Ozogamicin, Enfortumab vedotin, Trastuzumab deruxtecan, Sacituzumab govitecan, Brentuximab Vedotin, Moxetumomab pasudotox, Polatuzumab Vedotin, Belantamab Mafodotin, loncastuximab tesirine and Tisotumab vedotin."

DRUG

Antineoplastic and immunomodulating agents other than Antibody-Drug Conjugate

We would like to include other common cancer drug therapies such as chemotherapy, targeted therapy, immunotherapy and so on as a comparator group.

Trial Locations (1)

410000

Central South University, Changsha

All Listed Sponsors
lead

Central South University

OTHER