NCT05348460View on ClinicalTrials.gov

Effects of a Single Oral Dose of KETone Ester ON Exercise Performance in Patients With Chronic Heart Failure

NACompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

February 15, 2022

Primary Completion Date

July 1, 2023

Study Completion Date

July 1, 2023

Conditions
Heart Failure With Reduced Ejection FractionHeart Failure
Interventions
DIETARY_SUPPLEMENT

Ketone ester drink (DeltaG®, 500 mg/kg body weight)

In a double blind fashion, subjects will receive a ketone ester drink ór a taste-matched, isovolumic placebo drink and will then perform the 31P MRS exercise protocol. After 1-2 weeks, subjects will cross-over and repeat the 31P MRS exercise protocol, this time receiving the other treatment.

DIETARY_SUPPLEMENT

Taste-matched, isovolumic placebo drink

In a double blind fashion, subjects will receive a ketone ester drink ór a taste-matched, isovolumic placebo drink and will then perform the 31P MRS exercise protocol. After 1-2 weeks, subjects will cross-over and repeat the 31P MRS exercise protocol, this time receiving the other treatment.

Trial Locations (1)

9713GZ

University Medical Center Groningen, Groningen

All Listed Sponsors
collaborator

Netherlands Heart Foundation

OTHER

lead

University Medical Center Groningen

OTHER