Pharmacokinetics and Safety of 'CG-745 IV' and 'CG-750' in Healthy Male Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

December 16, 2019

Primary Completion Date

September 18, 2020

Study Completion Date

May 19, 2021

Conditions
Healthy
Interventions
DRUG

CG-745 IV Solution

CG-745 IV: Supplied as 125 mg/vial Administered intravenously, once, approximately 9 AM local time in fasted condition, over 60 min infusion

DRUG

CG-750 125mg capsule

CG-750 capsule: Supplied as 125 mg/capsule Administered orally, once, approximately 9 AM local time in fasted condition except for fed condition in Cohort 2, period 3

OTHER

PO Placebo

PO Placebo: Supplied as placebo capsule (same appearance as in CG-750 Administered orally, once, approximately 9 AM local time in fasted condition except for fed condition in Cohort 2, period 3

OTHER

IV Placebo: 0.9 % normal saline

IV Placebo: 0.9 % normal saline Administered intravenously, once, approximately 9 AM local time in fasted condition, over 60 min infusion

Trial Locations (1)

03080

Seoul National University Hospital, Seoul

Sponsors
All Listed Sponsors
lead

CrystalGenomics, Inc.

INDUSTRY