MSLN STAR-T Cells in the Treatment of Advanced Malignant Solid Tumors

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

April 14, 2022

Primary Completion Date

October 14, 2024

Study Completion Date

February 1, 2026

Interventions
BIOLOGICAL

MSLN STAR-T cells

Patients with advanced MSLN-positive solid tumors will be recruited, and autologous-derived MSLN-STAR-T cells will be infused intravenously at escalating doses of 1×10\^7-1×10\^8 MSLN-STAR-T cells. The CAR-T ratio will be monitored at predetermined times (day 0, day 4, day 7, day 10, day 14, day 28).

All Listed Sponsors
lead

Peking University

OTHER

NCT05344976 - MSLN STAR-T Cells in the Treatment of Advanced Malignant Solid Tumors | Biotech Hunter | Biotech Hunter