NCT05340231View on ClinicalTrials.gov

An Exploratory Study of Sequential Transarterial Chemoembolization With Lipiodol and Neoadjuvant Chemotherapy in the Treatment of Initial Unresectable Colorectal Cancer (CRC)

PHASE2Not yet recruitingINTERVENTIONAL

Enrollment

100

Participants

Timeline

Start Date

May 1, 2022

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2025

Conditions

Colorectal Cancer

Interventions

DRUG

TACE protocol

"Transarterial infusion chemotherapy: Oxaliplatin(85mg/m\^2)+Raltitrexed(3mg) Chemoembolization: Lipiodol emulsion (lipiodol 10ml+ Oxaliplatin 85mg +Lidocaine 1ml)，The endpoint for embolization was defined as stagnation of blood flow of the posterior mesenteric artery.~Intervention cycle：4W; Treatment times: 2. followed by mFOLFOX6"

DRUG

Neoadjuvant Chemotherapy

mFOLFOX6, Q2W

All Listed Sponsors

lead

Gang Wu

OTHER

NCT05340231 - An Exploratory Study of Sequential Transarterial Chemoembolization With Lipiodol and Neoadjuvant Chemotherapy in the Treatment of Initial Unresectable Colorectal Cancer (CRC) | Biotech Hunter | Biotech Hunter