Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD

PHASE2CompletedINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

May 19, 2022

Primary Completion Date

March 5, 2025

Study Completion Date

July 25, 2025

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG

Itepekimab SAR440340

Pharmaceutical form: solution for injection in pre-filled syringe; Route of administration: subcutaneous

Trial Locations (28)

2400

Investigational Site Number : 2080001, Copenhagen

2650

Investigational Site Number : 0560001, Edegem

Investigational Site Number : 2080002, Hvidovre

9000

Investigational Site Number : 2080003, Aalborg

15801

Clinical Research Associates of Central PA - Dubois- Site Number : 8400011, DuBois

19104

Penn Medicine: University of Pennsylvania Health System- Site Number : 8400016, Philadelphia

22927

Investigational Site Number : 2760001, Großhansdorf

31224

Investigational Site Number : 2760004, Peine

33125

University of Miami UHealth Tower- Site Number : 8400015, Miami

48088

Pulmonary and Medicine Associates- Site Number : 8400020, Warren

66160

University of Kansas Medical Center- Site Number : 8400004, Kansas City

73120

Allergy, Asthma and Clinical Research- Site Number : 8400010, Oklahoma City

75390

University of Texas - Southwestern Medical Center- Site Number : 8400014, Dallas

77555

University of Texas Medical Branch- Site Number : 8400001, Galveston

79106

Investigational Site Number : 2760005, Freiburg im Breisgau

80206

National Jewish Health Medical Center- Site Number : 8400012, Denver

90509

UCLA Medical Center - Harbor- Site Number : 8400006, Torrance

02114

Harvard Medical School - Massachusetts General Hospital (MGH) - Medical Practice Evaluation Center (MPEC)- Site Number : 8400007, Boston

87015-000

Hospital Parana- Site Number : 0760009, Maringá

90610-000

Hospital São Lucas da PUCRS - Porto Alegre - Avenida Ipiranga- Site Number : 0760003, Porto Alegre

13034-685

Hospital e Maternidade Celso Pierro - PUC-Campinas- Site Number : 0760004, Campinas

15501-405

Integral Pesquisa e Ensino- Site Number : 0760006, Votuporanga

01323-001

Hospital Beneficência Portuguesa de São Paulo- Site Number : 0760005, São Paulo

9713 GR

Investigational Site Number : 5280001, Groningen

M23 9QZ

Investigational Site Number : 8260003, Wythenshawe

W2 1NY

Investigational Site Number : 8260004, London

NG5 1PB

Investigational Site Number : 8260001, Nottingham

L9 7AL

Investigational Site Number : 8260002, Liverpool

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Regeneron Pharmaceuticals

INDUSTRY

lead

Sanofi

INDUSTRY