49
Participants
Start Date
May 31, 2022
Primary Completion Date
December 31, 2026
Study Completion Date
March 31, 2027
CD19-targeted chimeric antigen receptor T-cell
"Drug: Fludarabine~patients will receive a lymphodepletion chemotherapy with Fludarabine 25 mg/m2/day IV for 3 days on Day-5 to Day-3(a safe window for a small subset of patients will be D -7 to D -3).~Drug: Cyclophosphamide~patients will receive a lymphodepletion chemotherapy with cyclophosphamide 300 mg/m2/day IV for 3 dys Day-5 to Day-3(a safe window for a small subset of patients will be D -7 to D -3).~Biological: CD19 CAR-T~CD19 CAR-T cells will be administered using as a single dose at 0.1-9\*10\^6 cells/kg on Day 0 after completion of the lymphodepletion chemotherapy. The body weight calculated for PL001 dose is the actual body weight on the day of leukapheresis."
NOT_YET_RECRUITING
Chi Mei Medical Center, Tainan City
RECRUITING
Taipei Medical University - Taipei Medical University Hospital, Taipei
RECRUITING
National Taiwan University Hospital, Taipei
RECRUITING
Taipei Veterans General Hospital, Taipei
RECRUITING
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City
Pell Bio-Med Technology Co., Ltd.
INDUSTRY