Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 6, 2022

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Myelofibrosis; AnemiaAnemiaMyelofibrosisMyelofibrosis Due to and Following Polycythemia VeraPrimary MyelofibrosisPost-essential Thrombocythemia MyelofibrosisMyelodysplastic Syndromes
Interventions
DRUG

DISC-0974

DISC-0974 is administered subcutaneously.

Trial Locations (15)

10021

RECRUITING

Memorial Sloan Kettering Cancer Center, New York

10029

RECRUITING

Icahn School of Medicine at Mount Sinai, New York

17325

WITHDRAWN

Sargon Research - Pennsylvania Cancer Specialists and Research Center, Gettysburg

19104

RECRUITING

University of Pennsylvania, Philadelphia

27157

RECRUITING

Atrium Health Wake Forest Baptist, Winston-Salem

32224

RECRUITING

Mayo Clinic Jacksonville, Jacksonville

44195

RECRUITING

Cleveland Clinic, Cleveland

44718

TERMINATED

Gabrail Cancer Center Research, Canton

48109

RECRUITING

University of Michigan, Ann Arbor

53226

RECRUITING

Medical College of Wisconsin, Milwaukee

55905

RECRUITING

Mayo Clinic Rochester, Rochester

63110

RECRUITING

Washington University St.Louis, St Louis

77030

RECRUITING

MD Anderson, Houston

97239

RECRUITING

Oregon Health and Science University, Portland

98109

RECRUITING

University of Washington, Seattle

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Disc Medicine, Inc

INDUSTRY

NCT05320198 - Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia | Biotech Hunter | Biotech Hunter