A Phase II Study of AK104 Plus Lenvatinib and TACE in HCC

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 28, 2022

Primary Completion Date

August 15, 2023

Study Completion Date

June 30, 2025

Conditions
Unresectable, Non-metastatic Hepatocellular Carcinoma
Interventions
BIOLOGICAL

AK104

Subjects will receive AK104 until disease progression or for a maximum of 24 months

DRUG

Lenvatinib

Subjects will receive lenvatinib until disease progression or for a maximum of 24 months

PROCEDURE

TACE

On demand TACE

Trial Locations (5)

100034

The First Hospital of Beijing University, Beijing

250117

Shandong Cancer Hospital, Jinan

410013

Hunan Cancer Hospital, Changsha

450003

Henan Cancer Hospital, Zhengzhou

510515

Nanfang Hospital, Southern Medical University, Guangzhou

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Akeso

INDUSTRY

NCT05319431 - A Phase II Study of AK104 Plus Lenvatinib and TACE in HCC | Biotech Hunter | Biotech Hunter