187
Participants
Start Date
May 23, 2022
Primary Completion Date
September 30, 2023
Study Completion Date
September 30, 2023
Sacral NeuroModulation
Sacral Neuromodulation group will include up-to 20 patients with major LARS. Medtronic Interstim system will be used, including 2 week trial device.
Trans-Anal Irrigation
Trans-Anal irrigation group will include up-to 20 patients with major LARS. Specific system will be agreed with the patient, depending on eligibility and preference.
Optimised Conservative Management
Optimised conservative management will include up-to 30 patients with major LARS. They will be provided with a resource booklet which includes dietary and lifestyle advice as well as exercises that can be undertaken independently.
University Hospital Southampton NHS Foundation Trust, Southampton
Leeds Teaching Hospital NHS Trust, Leeds
Julie Cornish, Cardiff
Royal Gwent Hospital, Newport
Collaborators (1)
University of Leeds
OTHER
Aneurin Bevan University Health Board
OTHER
University Hospital Southampton NHS Foundation Trust
OTHER
Bowel Research UK
UNKNOWN
The Leeds Teaching Hospitals NHS Trust
OTHER
Cardiff and Vale University Health Board
OTHER_GOV