NCT05315999View on ClinicalTrials.gov

Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 3, 2022

Primary Completion Date

December 18, 2024

Study Completion Date

December 18, 2024

Conditions
NauseaVomitingPainAdvanced Cancer
Interventions
DRUG

Palonosetron Hydrochloride

Palonosetron (500µg): single dose per os 1-2 hours before the start of opioid-therapy (WHO II \& III)

DRUG

Placebo

Placebo: single dose per os 1-2 hours before the start of opioid-therapy (WHO II \& III)

Trial Locations (1)

D-79106

Clinic for Palliative Care, Medical Center, University of Freiburg, Freiburg im Breisgau

All Listed Sponsors
lead

Gerhild Becker

OTHER