Cardiac Outcomes With Near-Complete Estrogen Deprivation

Adenosine stress CMR test with contrast to include cardiovascular structural and functional measures including myocardial blood flow through quantitative perfusion mapping. Participants will have 3 stress tests as a part of this research. These tests will happen when at the beginning of the study, and then every year for 2 years.

A 12-lead electrocardiogram will be done when at the start of the study and at the participant's 2 year stress test to look at the electrical signals of your heart.

Contrasted coronary CT angiography will be performed for visual and quantitative analysis of coronary artery plaque burdens.

10 teaspoons of blood will be withdrawn at every visit that participants receive a stress test. Participants may have up to six blood draws associated with each imaging visit.

A general health status survey with 10 questions and should take about 5-10 minutes to finish. This survey is related to research.