Nonalcoholic Fatty Liver Disease - Intermittent Calorie Restriction (FLICR) Study

NACompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

March 7, 2022

Primary Completion Date

December 6, 2023

Study Completion Date

December 6, 2023

Conditions
Nonalcoholic Fatty LiverNonalcoholic Steatohepatitis
Interventions
BEHAVIORAL

Intermittent calorie restriction

Recipes will be provided with suggestions of meals that would not exceed the calorie restriction. For the remaining 5 days of the week, they will receive instructions and recipes that follows the Korean Dietary Reference Intakes (KDRIs), with an intake limit of 2,000 kcal/day for women and 2,500 kcal/day for men. The percentage of energy (E%) from different macronutrients in the recipes will be 45-60 E% carbohydrates, 25 E% fat and 10-20 E% protein.

BEHAVIORAL

Standard of care

They will receive individualized guidance from a hepatologist on how to choose a healthy diet, to reduce the intake of sweets and saturated fatty acids, increase sources of unsaturated fat, avoid large portions, and to regularly eat 3 meals per day. Each participant will be provided a written summary of the dietary advice.

Trial Locations (1)

07985

Ewha Womans University College of Medicine, Seoul

All Listed Sponsors
lead

Ewha Womans University Mokdong Hospital

OTHER