Empagliflozin in Acute Heart Failure

PHASE4RecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

December 22, 2022

Primary Completion Date

December 31, 2026

Study Completion Date

February 28, 2027

Conditions
Acute Heart FailureChronic Kidney Diseases
Interventions
DRUG

Empagliflozin 25 MG

Patients who fulfill the inclusion criteria will receive an intravenous dose of 1.0-1.5 mg/kg of furosemide (≤120 mg) and urine output will be monitored for three hours. Those with a urine output \< 300 ml in the first two hours post furosemide administration will receive a single oral dose of 25 mg of empagliflozin. Two hours after taking empagliflozin, patients will receive a second intravenous dose of 1.0-1.5 mg/kg of furosemide with another timed urine collection at three hours. Empagliflozin will then be continued daily for five days or until hospital discharge, unless the treating physician considers this not to be clinically appropriate.

Trial Locations (1)

Unknown

RECRUITING

Research Institute of the McGill University Health Center, Montreal

All Listed Sponsors
lead

McGill University Health Centre/Research Institute of the McGill University Health Centre

OTHER