NCT05304351View on ClinicalTrials.gov

Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

1,516

Participants

Timeline

Start Date

February 2, 2022

Primary Completion Date

June 30, 2026

Study Completion Date

March 6, 2032

Conditions
Herpes ZosterShingles
Interventions
BIOLOGICAL

Amezosvatein Antigen High Dose Arm A

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

BIOLOGICAL

Amezosvatein Antigen Low Dose Arm B

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

BIOLOGICAL

Shingrix

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

BIOLOGICAL

Amezosvatein Adjuvant Dose Arm D

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

BIOLOGICAL

Amezosvatein Adjuvant Dose Arm F

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

BIOLOGICAL

Amezosvatein Adjuvant Dose Arm H

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

BIOLOGICAL

Amezosvatein Adjuvant Dose Arm J

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

BIOLOGICAL

Amezosvatein Adjuvant Dose Arm L

Suspension for injection administered intramuscularly (IM) in the deltoid region of the non-dominant arm in Month 0 and Month 2 per study schedule

Trial Locations (14)

33134

Curevo Investigational Site, Coral Gables

33616

Curevo Investigational Site, Tampa

37909

Curevo Investigational Site, Knoxville

40509

Curevo Investigational Site, Lexington

60523

Curevo Investigational Site, Oak Brook

66219

Curevo Investigational Site, Lenexa

67114

Curevo Investigational Site, Newton

73013

Curevo Investigational Site, Edmond

75251

Curevo Investigational Site, Dallas

76040

Curevo Investigational Site, Euless

78745

Curevo Investigational Site, Austin

84107

Curevo Investigational Site, Salt Lake City

85281

Curevo Investigational Site, Tempe

89119

Curevo Investigational Site, Las Vegas

All Listed Sponsors
lead

Curevo Inc

INDUSTRY