Individualized Antibiotic Therapy in Children With Acute Uncomplicated Febrile Urinary Tract Infection

PHASE4CompletedINTERVENTIONAL
Enrollment

408

Participants

Timeline

Start Date

April 1, 2022

Primary Completion Date

February 29, 2024

Study Completion Date

June 8, 2024

Conditions
Febrile Urinary Tract Infection
Interventions
OTHER

Individualized antibiotic therapy

Individualized antibiotic therapy is based on the duration of illness after treatment initiation, as the antibiotic therapy can be stopped three days after the participant has become healthy. The participant is classified as healthy if he/she is afebrile (\<38.0 °C), has experienced significant clinical improvement, and have no flank pains or dysuria.

OTHER

Standard antibiotic therapy

Standard antibiotic therapy is 10 days of antibiotic therapy regardless of the duration of illness after treatment initiation.

Trial Locations (8)

2100

Copenhagen University Hospital Rigshospitalet, Copenhagen

2650

Copenhagen University Hospital Hvidovre, Hvidovre

2730

Copenhagen University Hospital Herlev, Herlev

3400

Copenhagen University Hospital Hillerød, Hillerød

4000

Copenhagen University Hospital Roskilde, Roskilde

4200

Copenhagen University Hospital Slagelse, Slagelse

4300

Copenhagen University Hospital Holbæk, Holbæk

4800

Copenhagen University Hospital Nykøbing Falster, Nykøbing Falster

All Listed Sponsors
collaborator

Hvidovre University Hospital

OTHER

lead

Rigshospitalet, Denmark

OTHER